From Annotated Genomes to Metabolic Flux Models and Kinetic Parameter Fitting
نویسندگان
چکیده
منابع مشابه
From annotated genomes to metabolic flux models and kinetic parameter fitting.
Significant advances in system-level modeling of cellular behavior can be achieved based on constraints derived from genomic information and on optimality hypotheses. For steady-state models of metabolic networks, mass conservation and reaction stoichiometry impose linear constraints on metabolic fluxes. Different objectives, such as maximization of growth rate or minimization of flux distance ...
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About the Authors, Paper: Douglas M. Bates is with the Department of Statistics at the University of Wisconsin. Donald G. Watts is a member of the Department of Mathematics and Statistics, Queen's University at Kingston. The work reported on was supported by the National Science Foundation in the United States and the Natural Sciences and Engineering Research Council of Canada. We consider syst...
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ژورنال
عنوان ژورنال: OMICS: A Journal of Integrative Biology
سال: 2003
ISSN: 1536-2310,1557-8100
DOI: 10.1089/153623103322452413